Researchers from NIA, Harvard, USC, UCLA and more find additional evidence that epigenetic age predicts mortality
"Epigenetic clock predicts life expectancy" - Science Daily. 9/28/2016.
Scientists from a consortium of 25 institutions analyzed DNA blood samples collected from 13,000-plus individuals to predict mortality. Their analyses used a range of molecular methods, including an 'epigentic clock' developed by PI and UCLA geneticist Steve Horvath. "We were stunned to see that the epigenetic clock was able to predict the lifespans of Caucasians, Hispanics and African-Americans," said first author Brian Chen, a postdoctoral fellow at the National Institute on Aging. "This rang true even after adjusting for traditional risk factors like age, gender, smoking, body-mass index, disease history and blood cell counts." Horvath says the research yields valuable clues about human aging that can help in the development of "targeted methods to slow the process."