Trojanowski et al. find "proteinopathies" may contribute to many old-age neurodegenerative diseases

Trojanowski et al. find "proteinopathies" may contribute to many old-age neurodegenerative diseases

NIA Aging Centers News Reference

"Rethinking neurodegenerative disease treatment: Target multiple pathological proteins" - EurekAlert!. 07/05/2018.

Rather than targeting solely the primary pathological proteins of a given neurodegenerative disease, a new study by senior author John Trojanowski and colleagues suggests that a better strategy might be to target "many of these disease-related aggregated proteins affecting most older patients across a full spectrum of clinical and neuropathological presentations." He says this approach offers "additional leverage to find ways to detect patients' specific proteinopathies with increasingly sophisticated biomarker and imaging technologies."

Researcher Profile:
John Q. Trojanowski (U-Penn)

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